Everything about Glycoalkaloid totally explained
Glycoalkaloids are a family of
poisons commonly found in the plant species
Solanum dulcamara (
nightshade).
(External Link
) There are several glycoalkaloids (alkaloids + sugars) that are potentially toxic. A prototypical glycoalkaloid is called
solanine (sugar [solanose] + alkaloid [solanidine] = solanine), which is found in
potatoes. The alkaloidal portion of the glycoalkaloid is also generically referred to as an
aglycone. The intact glycoalkaloid is poorly absorbed from the
GI tract but causes GI irritation. The aglycone is absorbed and is believed to be responsible for observed nervous system signs. Glycoalkaloids are
bitter tasting, and produce a burning irritation in the back of the
mouth and side of the
tongue when eaten.
Laboratory diagnosis: although not routinely available, detection of alkaloids in tissues or urine is possible.
Sale of a glycoalkaloid-based
treatment marketed by Lane Labs USA Inc. for prevention of
skin cancer was banned by the FDA in 2004 as an unapproved
drug. Similar glycoalkaloid
gels are now marketed as
exfoliants.
Further Information
Get more info on 'Glycoalkaloid'.
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